WIM Ject® for mRNA
WIM Ject® – engineered for extreme cold: reliability at -80°C for sensitive mRNA and other advanced therapies
mRNA and other advanced therapies represent a breakthrough in treating complex diseases, with potential applications in infectious disease prevention, cancer treatment, and genetic disorder management. These therapies, such as mRNA vaccines, require extreme low-temperature storage, often down to -80°C, to maintain stability and effectiveness.: These temperatures has brought new challenges for the primary packaging.
WIM Ject®is specifically engineered for the storage and delivery of mRNA and other advanced therapies that require ultra-low temperatures. Made from cyclic olefin copolymer (COC), it remains optically clear and mechanically stable even after freezing. Its FM257 rubber plunger ensures a reliable seal, even at extreme temperatures.
A specialized siliconization minimizes subvisible particles, preserving the safety and quality of the drug. Thanks to precise manufacturing, the syringe also offers excellent stability for lipid nanoparticles (LNP), supporting the long-term efficacy of mRNA therapies.
WIM Ject® - The smart solution for freezing precision
Safe and reliable
WIM Ject® offers maximum safety for mRNA and other high-tech therapies at extremely low temperatures. Its robust COC material and FM 257 rubber ensure a reliable seal, even after multiple freeze-thaw cycles. The cross-linked siliconization reduces particles and eliminates leachable silicone, ensuring cleaner and safer delivery. Unlike glass, it is shatter resistant and ideal for sensitive, critical applications.
Convenient
The WIM Ject® COC syringe offers maximum efficiency and easy handling. All components are manufactured at Wirthwein Medical, which makes logistics and quality assurance considerably easier. The pre-sterilized system enables seamless filling and reduces process steps. Customizable designs and standardized packaging facilitate integration into existing production lines. A comprehensive regulatory package also speeds up market approval.
Perfect fit
Utilizing most advanced production technology, it achieves tight dimensional precision with minimal product variability, critical for maintaining syringe integrity under extreme conditions. WIM Ject® offers lower protein adsorption compared to glass, providing exceptional stability of lipid nanoparticles (LNP) for mRNA and similar formulations.
Injection treatments for injection therapies with WIM Ject®
- mRNA vaccines and therapies
- viral vectors (AVV)
- cell- and gene therapies
- other advanced therapies requiring extreme cold temperate storage
WIM Ject® – A one-stop solution that offers you numerous benefits
Standard packaging for efficient high-speed filling
- sterilization - Ready for Filling: the syringes are pre-sterilized with gamma rays and ready for filling
- quality control: stringent quality control
- compatible: compatible for high speed filling: the ISO compliant packaging supports wide range of filling machines
- clean room production: Extremely low contamination: production is fully integrated in ISO7 cleanroom
- large yearly capacity: multiple fully automated, highly advanced production lines
- delivery: All components from a single source, optimized purchase quantities & delivery times
- second source: Identical materials, robust supply chain, large quantities available
Simple and practical system from a single source: All syringe components from one source
- filling volume: 1 ml (market standard)
- COC material 6013: minimal interactions, high protein & mRNA stability, similar shrinkage to rubber
- FM257 plunger & tip cap: optimal sealing, only one rubber material in contact with the active substance
- cross-linked reactive silicone: fewer subvisible particles, low content of leachable silicone, minimal risk of incompatibility
- precision: high dimensional accuracy, minimal variability, consistent top quality
- cold resistance: stable after several freeze-thaw cycles
- customization: fast, cost-effective in-house customization possible
Contact
Tom Van Ginneken, Head of Business Development
“Modern mRNA and gene therapies place the highest demands on their packaging. The WIM Ject® syringe was specially developed for extreme cold conditions and offers maximum safety, stability and compatibility - essential for the long-term efficacy of sensitive drugs.“
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